Lung Cancer Treatment Options
Lung Cancer Treatment Options
At diagnosis, patients can be divided into 3 treatment groups based on the
stage of the cancer:
Non-small cell lung cancer that can be treated with surgery.
Stage 0, stage I, and stage II non-small cell lung cancer can often be
removed by surgery. Radiation therapy may be used to treat patients who have
other medical problems and cannot have surgery.
Non-small cell lung cancer that has spread to nearby tissue or to
lymph
nodes.
Non-small cell lung cancer that has spread to nearby tissue or to lymph nodes
can be treated with one of the following:
- -Radiation therapy alone.
- -Radiation therapy and chemotherapy or other kinds of treatment.
- -Surgery alone.
Non-small cell lung cancer that has spread to other parts of the body
or to another lobe of the lungs.
Radiation therapy may be used as palliative therapy to shrink the cancer and
to relieve pain in patients who have non-small cell lung cancer that has
spread to other parts of the body. Chemotherapy may be used to treat some
patients.
Four types of standard treatment are used:
Surgery
Three types of surgery are used:
- -Wedge resection: A surgical procedure to remove a triangle-shaped slice of tissue. It may be used to remove a tumor and a small amount of normal tissue around it.
- -Lobectomy: A surgical procedure to remove a whole lobe (section) of the lung.
- -Pneumonectomy: Surgery to remove one whole lung.
Chemotherapy
Chemotherapy is a cancer treatment that uses drugs to stop the growth of
cancer cells, either by killing the cells or by stopping the cells from
dividing. When chemotherapy is taken by mouth or injected into a vein or
muscle, the drugs enter the bloodstream and can reach cancer cells throughout
the body (systemic chemotherapy). When chemotherapy is placed directly into
the spinal column, an organ, or a body cavity such as the abdomen, the drugs
mainly affect cancer cells in those areas (regional chemotherapy). The way
the chemotherapy is given depends on the type and stage of the cancer being
treated.
Radiation therapy
Radiation therapy is a cancer treatment that uses high-energy x-rays or other
types of radiation to kill cancer cells. There are two types of radiation
therapy. External radiation therapy uses a machine outside the body to send
radiation toward the cancer. Internal radiation therapy uses a radioactive
substance sealed in needles, seeds, wires, or catheters that are placed
directly into or near the cancer.
Radiosurgery is a method of delivering radiation directly to the tumor with
little damage to healthy tissue. It does not involve surgery and may be used
to treat certain tumors in patients who cannot have surgery.
The way the radiation therapy is given depends on the type and stage of the
cancer being treated.
Laser therapy
Laser therapy is a cancer treatment that uses a laser beam (a narrow beam of
intense light) to kill cancer cells.
Other types of treatment and prevention are being tested in clinical trials.
These include the following:
Photodynamic therapy (PDT)
Photodynamic therapy (PDT) is a cancer treatment that uses a drug and a
certain type of laser light to kill cancer cells. A drug that is not active
until it is exposed to light is injected into a vein. The drug collects more
in cancer cells than in normal cells. Fiberoptic tubes are then used to
deliver the laser light to the cancer cells, where the drug becomes active
and kills the cells. Photodynamic therapy causes little damage to healthy
tissue. It is used mainly to treat tumors on or just under the skin or in the
lining of internal organs, such as the lungs and the esophagus.
Chemoprevention
Chemoprevention is the use of drugs, vitamins, or other substances to reduce
the risk of developing cancer or to reduce the risk cancer will recur (come
back).
New treatments
New combinations of treatments are being studied in clinical trials.
Lung Cancer Treatment News
Treatment Gives Lung Cancer Patients With Inoperable Tumors Two Years Or More
18 Mar 2008 at 1:00am
Radiofrequency ablation (RFA) -- an interventional treatment that "cooks" and kills lung cancer tumors with heat -- greatly improves survival time from primary or metastatic inoperable lung tumors, according to a study released at the Society of Interventional Radiology's 33rd Annual Scientific Meeting.
European Medicines Agency (EMEA) Approves ALIMTAŽ (pemetrexed For Injection) For Use In Lung Cancer Treatment
14 Apr 2008 at 2:51am
OnApril 11, 2008, an announcement by Eli Lilly and Company (NYSE:LLY) indicated that European health authorities have approved theuse of ALIMTAŽ (pemetrexed for injection) for a histologically-baseduse in the first-line treatment of advanced non-small-cell lung cancer(NSCLC), the most common form of lung cancer.
Determining genetic signature of lung tumors can help guide treatment
19 May 2008 at 10:00pm
(Massachusetts General Hospital) The first US clinical trial using genetic screening to identify lung tumors likely to respond to targeted therapies supports the use of those drugs as first-line treatment rather than after standard chemotherapy has failed.
Treatment for mild asthma leads to improved lung function
9 Mar 2008 at 10:00pm
A study by the Woolcock Institute of Medical Research in Sydney is the first to demonstrate that in patients with very mild or well-controlled asthma, regular treatment with low dose ICS leads to significantly better day-to-day lung function.
Mutation Database Helps Personalized Treatment Of Lung Cancer - Online Compendium Matches EGFR Mutations With Clinical Outcomes
25 Apr 2008 at 7:00am
A groundbreaking free tool to help oncologists choose the best therapies for patients with non-small-cell lung cancer has been launched this week by scientists at the 1st European Lung Cancer Conference jointly organized by the European Society for Medical Oncology (ESMO) and the International Association for the Study of Lung Cancer (IASLC) in Geneva, Switzerland.
Local Researchers Look To Improve Treatment For Lung Cancer Patients, UK
11 Mar 2008 at 3:59am
Doctors from around the UK are taking part in one of the world's largest lung cancer clinical trials investigating how a blood thinning drug might help prevent blood clots in lung cancer patients.
ALIMTAŽ (pemetrexed For Injection) Receives European Approval For Histologically-Based Use In First-Line Treatment Of Most Common Lung Cancer
21 Apr 2008 at 2:30am
Eli Lilly and Company (NYSE: LLY) announced that European health authorities have approved the use of ALIMTAŽ (pemetrexed for injection) for a histologically-based use in the first-line treatment of advanced non-small-cell lung cancer (NSCLC), the most common form of lung cancer.
Mutation database helps personalized treatment of lung cancer
24 Apr 2008 at 10:00pm
(European Society for Medical Oncology) A groundbreaking free tool to help oncologists choose the best therapies for patients with non-small-cell lung cancer has been launched this week by scientists at the 1st European Lung Cancer Conference jointly organized by the European Society for Medical Oncology and the International Association for the Study of Lung Cancer in Geneva, Switzerland.
Alfacell's ONCONASE(R) Shows Potential As Radiation Sensitizer For Lung Cancer Treatment
15 Apr 2008 at 2:30am
Alfacell Corporation (Nasdaq: ACEL) announced that Dr. Intae Lee with the University of Pennsylvania has reported that Alfacell's ONCONASE (ranpirnase) could be a promising radiation sensitizer for lung cancer treatment. Dr.
Genetic Test For Lung Cancer Recurrence?
20 May 2008 at 7:00am
The goal of developing reliable genetic tests to guide lung cancer treatment has taken a step forward. Researchers at Columbia University recently evaluated the ability of five high-risk genetic profiles, or signatures, to predict the likelihood that cancer would recur in patients whose non-small cell lung cancer was caught early and surgically removed.
Vaccine May Treat Lung Cancer
25 Apr 2008 at 2:47am
An experimental vaccine that works by training the immune system to kill specific tumor cells is showing promise for the treatment of early lung cancer, researchers report.
Amrubicin(R) Receives FDA Orphan Drug Designation For The Treatment Of Small Cell Lung Cancer
27 Mar 2008 at 7:00am
Celgene Corporation (NASDAQ: CELG) announced that Amrubicin has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for the treatment of small cell lung cancer.
Vicus Therapeutics Records Last Patient Visit Of Phase 2, VT-122 Trial For The Treatment Of Cachexia In Patients With Advanced Lung Cancer
1 May 2008 at 2:47am
Vicus Therapeutics, LLC, a biopharmaceutical company focused on oncology supportive care, announced today the completion of the last patient visit in its study VT1-CAX-001, a Phase 2 trial of VT-122. The compound was tested for the treatment of cachexia in weight losing subjects with Stage IV, non-small cell lung cancer (NSCLC).
New treatment could reduce chronic lung disease in premature babies
28 Apr 2008 at 10:00pm
A less traumatic way of delivering surfactant, a lung lubricant that premature babies need to help them breathe, could reduce the incidence of respiratory problems they'll have later, Medical College of Georgia physicians say.
New conference tackles the tough questions in lung cancer
3 Apr 2008 at 10:00pm
Experts from around the world are gathering in Geneva next month at a new conference that aims to improve lung cancer treatment and answer unsolved questions about a disease that kills 1.5 million people each year.