When a patient is diagnosed with metastatic disease the primary site of the cancer is usually, but not always, evident. When the origin of the cancer is not identified it is described as a Cancer of Unknown Primary site, or CUP. Each year in the UK over 10,000 people are diagnosed with CUP.

(American Association for Cancer Research) Physiological changes associated with the metabolic syndrome may play a role in the risk of postmenopausal breast cancer, according to study results published in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.

(Memorial Sloan-Kettering Cancer Center) A new study by researchers at Memorial Sloan-Kettering Cancer Center reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone -- the two most prominent sites of lung cancer relapse. The study will be published online in the journal Cell on July 2.

The recent release of two large randomized trials suggests that if there is a benefit of screening, it is, at best, small, says a new report in CA: A Cancer Journal for Clinicians. Authored by Otis W. Brawley, M.D. of the American Cancer Society and Donna Ankerst, Ph.D. and Ian M. Thompson, M.D.

(American Cancer Society) The recent release of two large randomized trials suggests that if there is a benefit of screening, it is, at best, small, says a new report in CA: A Cancer Journal for Clinicians.

(Journal of the National Cancer Institute) Several statistical and biological issues need to be addressed in order to improve biomarker identification for early detection of cancer, according to a commentary published online July 2 in the Journal of the National Cancer Institute.

Today the Lance Armstrong Foundation and the American Cancer Society announced they have formed a first-of-its-kind partnership to empower and support survivors all over the world and aggressively address the global cancer burden.

(Journal of the National Cancer Institute) Certain mutations in the DNA of the hepatitis B virus are associated with the development of liver cancer and may help predict which patients with HBV infections are at increased risk of the disease, according to a large meta-analysis in the Journal of the National Cancer Institute, published online July 2.

Scientists discover novel mechanism that increases the risk of common colorectal cancer Finnish Academy Professors Lauri Aaltonen and Jussi Taipale have identified and described a mechanism whereby a single-base change in the human genome increases the risk of colorectal cancer.

A new method of attacking cancer cells, developed by researchers in Australia, has proved surprisingly effective in animal tests.

Smoking is such a well-known cause of lung cancer that many don't realize thousands who never smoked get the diagnosis. The great majority are women. Recent research shows it's really a different disease than smoking-related lung cancer. But those with the diagnosis say they suffer the same stigma.

(Johns Hopkins Medical Institutions) Cancer experts at Johns Hopkins say a study tracking 774 prostate cancer patients for a median of eight years has shown that a three-way combination of measurements has the best chance yet of predicting disease metastasis.

ATLANTA (AP) -- In a perverse twist of medical fate, Farrah Fawcett has become the poster girl for anal cancer, a rare disease often linked to a sexually transmitted virus....

A doctor accused of botching dozens of prostate cancer surgeries at a Veterans Administration hospital admitted Monday that he sometimes missed his target when implanting radioactive seeds, leaving patients with incorrect dosages.

Researchers at the Moores UCSD Cancer Center are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the disease.